Study: mRNA “Vaccine” Causes Inflammation after One Year

A Saudi study by A. Alghamdi et al titled “Altered Circulating Cytokine Profile Among mRNA-Vaccinated Young Adults: A Year‐Long Follow‐Up Study” posted on 9 April 2025 confirms that the so-called vaccine causes inflammation even a year after injection.

The paper is 16 pages long. The main text is about 14 pages, although about half of that are tables and figures.

A total of 84 subjects participated in this study with the mean age of 27.2 ± 12.3 years with 36 males and 48 females.

The pre-vaccination recruitment started in November 2020 over a five-month period. The post-vaccination recruitment started in November 2021 with an “average follow‐up duration of 14.1 ± 3.6 months for adolescents and 13.3 ± 3.0 months for adults”. The study measured the levels of 18 biomarkers.

The analysis breakdown includes gender, age group (adolescents and adults) and time after the last dose (4 months or less and 5 months or more).

In short, the study found that

…COVID‐19 vaccination resulted in an increase in cytokine levels, signifying continued immune system stimulation and response even 1 year after vaccination. … Additionally, this study observed that the interval following vaccination affects cytokine levels. These observations may be linked to the persistent production of spike protein and highly inflammatory nature of mRNA–lipid nanoparticle (LNP). The potential risks associated with a mRNA vaccine that prompts human cells to become targets for autoimmune responses cannot be thoroughly evaluated without precise knowledge of the distribution and behavior of LNPs and mRNA, along with the spike protein production dynamics.

For example, interleukin‐6 (IL6) is a cytokine (signalling protein) that is associated with inflammation. The overall median pre-vaccination level is 4.0pg/mL (Q1–Q3: 1.1–10.2) and post-vaccination level is 6.2pg/mL (Q1–Q3: 1.6–11.3). This increase is higher for males than females and, as expected, higher in adults than in adolescents.

As for interleukin‐1 beta (IL1β), another pro-inflammatory cytokine, the overall median pre-vaccination level is 17.2pg/mL (Q1–Q3: 9.6–24.2) and the post-vaccination level is 22.8pg/mL (Q1–Q3: 14.3–31.1). This increase is higher for females than males and, as expected, higher in adults than in adolescents.

As shown in Figure 1 reproduced below, “[t]he responses of biomarkers continued to be higher as compared to baseline level for most of the cytokines with the exception of MCSF and EGF”.

Figure 1: Log2 fold change in biomarkers postvaccination among select groups.

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